In all subjects, UA was not an independent risk factor for the non-renal outcome with the Cox proportional hazard model adjusted for underlying disease causing CKD, eGFR, urinary protein, systolic blood pressure, past history of cardiac disease, ACE inhibitors/ARBs, diuretics, statins, antiplatelets, age, sex, smoking, BMI, hemoglobin, and albumin. The gene discussed is ALB; the disease is heart disorder.