In all subjects, UA was not an independent risk factor for ESRD with the Cox proportional hazard model adjusted for underlying disease causing CKD, eGFR, urinary protein, systolic blood pressure, past history of cardiac disease, ACE inhibitors/ARBs, diuretics, statins, antiplatelets, age, sex, smoking, BMI, hemoglobin, and albumin. This evidence concerns the gene ALB and chronic kidney disease.