In contrast, circulating “immature OCN-expressing EPC” (CD34-/CD133+/KDR+/OCN+ cell) levels were significantly higher in patients with CAD than those without CAD (3.50 [2.42, 4.35] vs. 3.14 [1.00, 3.95] LN cell counts/100,000 counts, P = 0.04) (Fig 3A). This evidence concerns the gene KDR and coronary artery disorder.