In 2001, the Pancreatic Cancer Genetic Epidemiology group (PACGENE) identified susceptibility genes in linkage studies (27) and succeeded in finding an association of 2 genetic loci with pancreatic cancer 7p21.1 (HDAC9) and 21q22.3 (COL6A2) (28). The gene discussed is HDAC9; the disease is familial pancreatic carcinoma.