PLAT and early-onset autosomal dominant Alzheimer disease: In the 70 reviews, seven articles discussed the topic of blood‐brain barrier (BBB), followed by tPA with six articles, pericytes with five articles, angiogenesis/neurovascular coupling with four articles, Alzheimer's disease/astrocyte/matrix metalloproteinase (MMP) with three articles each, and up to 25 articles mentioning therapeutic strategies.