KDR and neoplasm: The mRNA expression levels of various RTK genes, including VEGFR-1, VEGFR-2, PDGFR-α, PDGFR-β, anaplastic lymphoma kinase (ALK), epidermal growth factor receptor (EGFR), ErbB2, and B-RAF were compared between the tumor and adjacent normal tissues collected from the patient (Figure 5).