ATM and CDH1-related diffuse gastric and lobular breast cancer syndrome: The OR of 8.01 and two fold increased risk at the lower end of the confidence interval supports an association of ATM PGVs with LBC, which is consistent with Lu et al. [23] This group identified six PGVs in ATM in 369 (1.63%) patients with LBC (OR = 3.50; 95%CI 1.10–9.73), although this is a lower frequency than in our study (4/134 (2.99%)).