Autoantibodies against the 60 kDa Ro (Ro60)/SSA ribonucleoprotein (TROVE2), which is a common member of extractable nuclear antigens and frequent target of humoral immunity, are usually detected in autoimmune diseases such as primary Sjogren's syndrome, systemic lupus erythematosus, and RA. Here, RO60 is linked to rheumatoid arthritis.