Our results are consistent with the latter study showing B7-H4 expression on another cell type of hematopoietic cells in GC, and we are the first to report the high expression of B7-H4 on tumor-infiltrating neutrophils in human GC tumors, which may emphasize the importance of B7-H4-associated pathway in tumor-related immune suppression. This evidence concerns the gene VTCN1 and neoplasm.