B7-H4 has been found to be overexpressed in several human cancer types, such as cervical cancer [12] and non-small-cell lung cancer [13], and has also been found to predict patient's survival in human esophageal squamous cell carcinoma [14], renal cell carcinoma [15], and ovarian cancer [16]. The gene discussed is VTCN1; the disease is renal cell carcinoma.