Statistical analysis showed that high expression of S100A11 and MMP-9 was positively correlated with the FIGO stage and lymph node metastasis of EOCs, suggesting that S100A11 and MMP-9 play important roles in the occurrence and development of EOCs and are closely associated with prognosis, thus suggesting a new therapeutic target for ovarian cancer. Here, MMP9 is linked to metastatic malignant neoplasm in the lymph nodes.