We conducted further survival analysis in three tumor locations and found that the expression of HOXA1 only has prognostic value in oropharyngeal cancer (P < 0.05), while no significant predictive value in hypopharyngeal and laryngeal cancer (p > 0.05) in TCGA-HNSC patients (Figures 5B–D). This evidence concerns the gene HOXA1 and oropharynx cancer.