After the intersection of the results of GSVA and GSEA, 14 mutual pathways mainly focusing on the following four aspects: neurotrophin, vesicular transport, protein export; Ubiquitin mediated proteolysis, Glycan biosynthesis; gap junction, adherens junction, focal adhesion, regulation of actin cytoskeleton; Pathways in cancer including WNT/ERBB/ NOTCH/TGF-beta. Here, BDNF is linked to cancer.