In MDA-MB-231 triple negative breast cancer cells, which are known to have a high invasive capacity, leptin did not induce autophagy (Figure 1) neither induced changes in proliferation or apoptosis (Figure 2), but increased cell migration, in agreement with previous reports (Dubois et al., 2014; Weichhaus et al., 2014; Juarez-Cruz et al., 2019). This evidence concerns the gene LEP and triple-negative breast carcinoma.