KIDINS220 and nervous system disorder: Homozygous mutations of KIDINS220/ARMS cause pregnancy terminations in humans (Mero et al., 2017), as well as the heterozygous truncation of KIDINS220/ARMS can lead to a neurological disorder named SINO syndrome (Josifova et al., 2016; Yang et al., 2018; Zhao et al., 2019).