UCP2 expression was shown to positively correlate with tumor grade in both the CGGA RNA-seq database containing 625 low-grade glioma samples and 388 high-grade glioma samples and the TCGA GBMLGG database containing 515 low grade and 152 high-grade glioma samples (p<0.05, Figure 1C). Here, UCP2 is linked to neoplasm.