It was shown that CXCL9, which is the ligand with the lowest affinity for CXCR3, has the function of regulating immune cell migration, differentiation, and activation, with contribution to tumor suppression (36, 37), which accounts for the suppression of CXCL9/CXCR3 on GC. This evidence concerns the gene CXCL9 and neoplasm.