Adzavon (14) et al. preliminarily detected differentially expressed genes and pathways in IgG4-related dacryoadenitis and lymphoma using gene expression profile microarray analysis, which mainly focused on the B cell receptor signaling pathway, the NF-κB signaling pathway, FcγR mediated phagocytosis, the FcεRI signaling pathway, the EB virus infection signaling pathway, and the cancer signaling pathway. The gene discussed is PPIB; the disease is cancer.