The Kaplan–Meier analysis showed that patients with high HMMR mRNA expression in the TCGA-HNSCC had a worse PFS than patients in the low expression group (HR = 1.470, 95% CI: 1.110–1.960, p = 0.008) (Supplementary Figure 1). Here, HMMR is linked to head and neck squamous cell carcinoma.