Ramanathan et al. [21] concluded in a study including 344 patients that although the magnitude of the systemic inflammatory response is greater following open surgery compared with laparoscopic resection, CRP threshold predictive of postoperative infective complications were similar on postoperative days 3 (180 mg/dL) and 4 (140 mg/dL) following both open and laparoscopic resection for colon cancer. The gene discussed is CRP; the disease is malignant colon neoplasm.