The results showed that the green fluorescence was predominantly concentrated in areas where atherosclerotic plaques develop, namely, the aortic arch (ApoE-/- (ND) and ApoE-/- (HD) mice, 10 weeks)) and throughout the aorta of ApoE-/- mice with advanced atherosclerosis (i.e., ApoE-/- (HD), 32 weeks) (Figures 5(a) and 5(b)). This evidence concerns the gene APOE and atherosclerosis.