The gene ZPR1 is known to interact with the triglyceride-associated gene APOA5 (Ueyama et al., 2015), which plays an important role in regulating plasma triglyceride levels, a major risk factor for coronary artery disease (CAD) (van der Harst and Verweij, 2018). The gene discussed is ZPR1; the disease is coronary artery disorder.