SOD3 and infection: However, pretreatment with LB1 significantly increased (P ≤ 0.05) the life-span of the mutants that are defective in sod-3, skn-1, or dbl-1 (Figures 5D–F) and showed no change, decreased or increased resistance to DT104 infection in the previous assay without LB1 pretreatment, respectively (Figure 3E).