CD4 and systemic lupus erythematosus: Among these IL-2-dependennt cytokines, CD8+ T cells produced greater amount of IL-13 (HC: 30.41 ± 2.36%, 1.51 ± 0.14%, p<0.0001; SLE: 37.91 ± 2.27%, 1.53 ± 0.22%, p<0.0001) and IFN-γ (HC: 46.00 ± 3.22%, 25.07 ± 6.89%, p=ns; SLE: 48.04 ± 4.46%, 29.53 ± 2.83%, p<0.01) than CD4+ T cells (Figures 2 and 3).