Of note, SLE CD8+ T cells produced greater amount of IL-13 (% positive cells: SLE: 37.91 ± 2.27%, HC: 30.41 ± 2.36%, p<0.05; MFI: SLE: 470.42 ± 27.39, HC: 396.67 ± 26.54, p<0.05) than healthy control CD8+ T cells (Figures 2 and 3A). This evidence concerns the gene CD8A and systemic lupus erythematosus.