As our previous study showed that the presence of TLS-B cells in the tumor microenvironment mainly favors intratumor CD4+ T cell clonal expansion (13), we analyzed the expression of 550 immune-related genes in sorted TIL CD4+ T cells from 26 NSCLC patients in relation to their TLS-B cell densities. Here, CD4 is linked to non-small cell lung carcinoma.