Type 2 diabetes with first time prescription (index date) of either DPP-4 inhibitors or SU fromContinuous treatment in same practiceMean age 64 (DPP-4) and 69 (SU)Excluded: use of both SU and DPP-4 inhibitor; insulin use at baseline or follow-up, or any other antidiabetic drugs except metformin. This evidence concerns the gene DPP4 and type 2 diabetes mellitus.