GCG and Hypoglycemia: Self-reported hypoglycaemia was a secondary safety endpoint, reported using patient diaries and transcribed into case report form. SH defiend as requiring assistance of another person to administer fast-acting carbohydrates, glucagon or other resuscitative action–reported as a medical event of special interest.Confirmed hypoglycaemia defined as SH or minor hypoglycaemia (<3.1mmol/L). Nocturnal hypoglycaemia defined as episodes occurring between 00:01 and 05:59h. Patients asked to check blood glucose whenever a hypoglycaemic episode was suspected.