Interestingly, similar membranous structures were observed in neurons from Drosophila with a Charcot-Marie-Tooth disease type 2A (CMT2A) MFN2 mutation (R364Wlike) that results in mitochondrial hyperfusion (El Fissi et al., 2018). This evidence concerns the gene MFN2 and Charcot-Marie-Tooth disease type 2A1.