However, in other studies, ABCG2 rs2231142 was associated with severe thrombocytopenia (Low et al., 2016), and patients carrying the ABCG2 rs2231142 AA genotype were more likely to develop thrombocytopenia, neutropenia, and HFS even after adjustment (Kim et al., 2013). The gene discussed is ABCG2; the disease is Decreased total neutrophil count.