E2F3 and hepatocellular carcinoma: In vitro, miR-503 overexpression repressed human umbilical vein endothelial cells (HUVECs) capillary tube formation, HCC cell proliferation and colony formation, and induced cell cycle arrest at G1 phase in HCC cells through inhibiting its targets, fibroblast growth factor-b (FGF2), VEGFA, cyclin D3 and E2F3 (Xiao et al., 2013; Zhou et al., 2013).