MALAT1 and pulmonary fibrosis: In contrary, in mouse model of pulmonary fibrosis induced by silica (Yan W. et al., 2017), miR-503 was reduced in fibrotic lung tissue and cells exposed to silica compared with control, but long non-coding RNA MALAT1 was upregulated, and MALAT1 regulated miR-503 expression by competitively binding to miR-503.