Based on the comprehensive coefficients (the total number of stars) obtained from the assessment, the top five selenoproteins are GPX4, SELENOP, SELENOK, SELENOT, and GPX1/SELENOM/SELENOS/SELENOW, which are consistent with the ranking of AD research correlation (the number of reports on each selenoprotein in AD-related research). This evidence concerns the gene GPX1 and Alzheimer disease.