This Scn8a mouse model harbors the germline knock-in mutation N1768D (D/+), a mutation identified in an SCN8A epilepsy patient that died of SUDEP (Wagnon et al., 2015; Lopez-Santiago et al., 2017; Ottolini et al., 2017; Sprissler et al., 2017; Wengert et al., 2019). This evidence concerns the gene SCN8A and epilepsy.