PARK7 and Parkinson disease: As the diagram illustrates in Fig. 6L, our findings suggest that the neuroprotective role of WA against PD is dependent on the relief of oxidative stress, the mitigation of STING-mediated neuroinflammation, the enhancement of mitochondrial function, and the reduction in apoptosis, which is mainly through DJ1-Nrf2-STING axis in dopaminergic neurons of SNc.