Similar patterns of markers (for example, IL7r, Sell, Tcf7, Ccl5, Pdcd1, Cxcr6, and Rgs1) correlated with latent time and overall transcriptional activity in NASH mice that received either treatment (Fig. 2a, b, Extended Data Fig. 6e, f). This evidence concerns the gene TCF7 and metabolic dysfunction-associated steatohepatitis.