PON1 and kidney disorder: The involvement of PON1 SNVs in dyslipidaemia, cardiovascular diseases, and mortality of the examined HD subjects may be summarized as follows: Low activity alleles of PON1 rs662 (A) and rs854560 (T) contribute to the higher prevalence of atherogenic dyslipidaemia diagnosed by the TG/HDL-cholesterol ratio ≥ 3.8 but are not related to untransformed parameters of serum lipid profile and dyslipidemic patterns established by K/DOQI for kidney disease patients39.