Although there was no direct proof that targeted inhibition of PLA2G7 could be helpful in COVID-19, it has been stated that inhibition of cytosolic phospholipase A2α (cPLA2α) significantly reduced viral replication of Human Coronavirus 229E (HCoV-229E) and Middle East respiratory syndrome coronavirus (MERS-CoV) infected cells38. This evidence concerns the gene PLA2G7 and COVID-19.