Seviour et al. revealed an activation function of miR-124 through binding to and inducing transcription on the p27 promoter region in breast and ovarian cancer cell lines.70 Costa et al. observed that miR-675-5p overexpression in normoxia promoted upregulation of some genes.71 Therefore, lncRNA H19-derived miR-675-5p might affect the PFKFB3-mediated glycolysis pathway and reprogram the glycolysis state in oral CAFs. The gene discussed is PFKFB3; the disease is ovarian carcinoma.