CSF1R and glioblastoma: Additionally, since TAMs have also been reported to be associated with angiogenesis, vasculogenic mimicry and revascularization after radiation in GBM xenografts, it will also be instructive to examine the synergistic effect of CSF-1R inhibitors with anti-angiogenic therapy, which was shown effective in high-grade serous ovarian cancer [80, 129, 162].