On the other hand, miR-504 was found to suppress the aggressive biological processes related with the mesenchymal phenotype of GBM primarily through negatively regulating FZD7-mediated Wnt–β-catenin pathway, and, correspondingly, low miR-504/FZD7 expression ratio was found as a mesenchymal subtype marker and prognostic indicator for GBM patients [76]. Here, FZD7 is linked to glioblastoma.