Specifically, we compared metabolomic profiles of 4 IDH non-mutant chondrosarcomas with 8 mutant IDH1 and 5 mutant IDH2 chondrosarcomas (Table 1) using targeted gas chromatography-mass spectrometry (GC/MS) and flow-injection tandem mass spectrometry (MS/MS) methods [10]. This evidence concerns the gene IDH1 and chondrosarcoma.