Moreover, it was also combined with the androgen receptor (AR) antagonist SHR3680 in patients with metastatic CRPC (mCRPC) (NCT03741712) and combined with SHR1701, inhibiting both programmed cell death ligand-1 (PD-L1) and transforming growth factor-β (TGF-β) II in advanced solid tumors and B-cell lymphomas (NCT04407741). The gene discussed is CD274; the disease is B-cell non-Hodgkin lymphoma.