PLEK and metabolic dysfunction-associated steatotic liver disease: Finally, top enriched terms for the genes most highly enriched in the polyA-selected chromatin-bound fraction include ribosomal protein, oxidative phosphorylation/mitochondria, non-alcoholic fatty liver disease, and mRNA-splicing (Table S2F); while the top enriched terms for the non-polyA-selected chromatin-bound PCGs included nucleosome assembly (primarily histone genes, whose transcripts are not poly-adenylated [45]), metal binding/zinc finger proteins, Pleckstrin homology domain, and DNA-binding (Table S2G).