Kaplan–Meier survival analysis indicated that HCC with a high expression of MRGBP had a worse overall survival (OS) (hazard ratio [HR] = 1.87 [1.31–2.66], P < .001), progression-free interval (HR = 1.47 [1.10–1.98], P = .010), and disease-specific survival (HR = 1.79 [1.14–2.80], P = .011) than HCC with low MRGBP expression (Fig. 2). This evidence concerns the gene MRGBP and hepatocellular carcinoma.