In addition, high MRGBP expression increased the immune infiltration levels in T helper cells, Tfh cells, NK CD56 bright cells, and Th2 cells and decreased immune infiltration in Th17 cells, DC, Tgd cells, cytotoxic cells, Tregs, pDCs, and iDCs in HCC. The gene discussed is MRGBP; the disease is hepatocellular carcinoma.