MRGBP and colorectal cancer: MRGBP can promote the proliferation of colorectal cancer cells by regulating the cell cycle, not apoptotic cells.[13] However, the expression level of MRGBP in colorectal cancer was not correlated with clinicopathological factors.[12] Scotto et al[15] showed that MRGBP was upregulated in cervical cancer cells as a consequence of the 20q gain.