Numerous studies have shown that YTHDF1 is overexpressed in various cancers, such as colorectal cancer 42, hepatocellular carcinoma 43, breast cancer 44, Merkel cell carcinoma 45, non-small cell lung cancer 46, and ovarian cancer 47, which are closely associated with an increased risk of these cancers. The gene discussed is YTHDF1; the disease is Merkel cell skin cancer.