The scatterplot of PTEN and Msi1 correlation was shown in Figure 4C. The levels of PTEN were negatively correlated with the expression of Msi1 in these clinical samples, indicating that PTEN downregulation occurred in human cervical carcinoma tissues (Figure 4A-4C, r=-0.3843, P=0.0264). The gene discussed is MSI1; the disease is cervical carcinoma.