MUC16 and endometriosis: Patients with pathologically confirmed endometriosis-associated OCCC are 4 to 8 years younger at diagnosis than those without endometriosis 53, 213, 214, and they are more likely to diagnosed at early-stage manifestations and have higher probability of optimal debulking, lower CA-125 levels, and a higher rate of platinum-sensitivity 19, 45, 46, 48.