A total of 309 genes in the magenta module (Supplementary Table S3) were significantly correlated with the following pathways: leukocyte transendothelial migration signaling pathway (ITGAM and ICAM1), TNF signaling pathway (ICAM1), and the Staphylococcus aureus infection (ITGAM and ICAM1), rheumatoid arthritis (ICAM1 and ITGAM), tuberculosis (ITGAM and CAMP), natural killer cell-mediated cytotoxicity (ICAM1 and TYROBP), and NF-kappa B signaling pathways (ICAM1). The gene discussed is ICAM1; the disease is tuberculosis.