Moreover, network-based meta-analysis revealed that the expression levels of ITGAM, CAMP, TYROBP and ICAM1 in CAD patients in GSE60993 and GSE66360 datasets were significantly higher than those in the control group, at the same time, the gene expression levels of ITGAM, CAMP and TYROBP in CAD patients in GSE61144 dataset were also significantly higher than those in the control group. This evidence concerns the gene ITGAM and coronary artery disorder.