HIF1A and preeclampsia: A combination of abnormal serum HIF-1α levels (higher than 1.45 MoM) and abnormal uterine artery Doppler PI (above the 95th percentile) was used as a predictive value for early-onset preeclampsia and its sensitivity, specificity, PPV, and NPV were 50%, 64.1%, 2.2%, and 98.8%, respectively (Table 3).