In addition to the two cytokines, the following variables were included in the model: donor sex and age, recipient sex and age, donor cause of death (cardiovascular accident, trauma), donor characteristics (ICU stay, diabetes, hypertension, hypotension, cardiac arrest, cold ischemia time), donor inotrope administered (none, one, two or more), time spent on the waiting list, number of HLA mismatches (HLA-A, -B, and -DR antigens), maximum panel-reactive antibody (PRA) level, immunologic risk and NITK338 (for kidney transplant only). The gene discussed is HLA-A; the disease is hypertensive disorder.