In fact, IL-6 and CXCL10 were not associated with kidney failure in univariate or multivariate analysis (Table 3, Supplementary Table S3) even if the prevalence of primary no function was significantly higher in high IL-6 category (Fig. 4) and a trend toward a higher percentage of chronic rejection (but not acute rejection) was evident in the high CXCL10 category. Here, IL6 is linked to kidney failure.