AVP and Cognitive impairment: Limitations of our study are sample size and selection bias for analyses, because ADH/TO-DKH mice with longer latency times (> 40 s) and ADH/WT mice with shorter latency times (< 20 s, similar to NT mice) on day 5 of the MWM were subjected to pathological examination in order to examine histopathological changes in mice with cognitive impairment.