EMCN and mucopolysaccharidosis: Consistently, flow cytometric analysis of the cells in metaphysis also showed a strong induction of tdTom expression in CD144+ cells (including vascular endothelial cells and endothelial progenitor cells)76 in p16tdTom mice after MPS treatment (Fig. 2e and f) although the percentages of CD144+ and Emcn+ endothelial cells were decreased in response to MPS treatment (Supplementary Fig. 2).