ATAD2 and hepatocellular carcinoma: Subsequently, ATAD2 was found overexpressed in various cancer types such as prostate cancer [14], hepatocellular carcinoma [15], lung cancer, breast cancer [16], gastric cancer [17] and ovarian cancer [18] and high expression of ATAD2 was approved as an indicator of poor prognosis and had a critical part in cell proliferation, apoptosis, invasion and migration.