Especially, Zhou et al. has proved the regulatory function of RPS4X on hepatocellular carcinoma’s tumorigenesis and metastasis by promoting the phosphorylation of S6K1 and eIF4E, which is indicative of the activation of mTOR signaling pathway and associated with mTOR-induced protein synthesis [21]. The gene discussed is RPS4X; the disease is hepatocellular carcinoma.