AR and myocardial infarction: The majority of experimental and clinical studies have focused on the effects of adenosine more on cardiomyocytes as compared to the coronary vasculature, as dissecting the effects of adenosine or AR activation on the coronary microcirculation from cardiomyocytes is challenging, given the causal relationship between injuries to the coronary vasculature and cardiomyocytes following the myocardial infarction.