To address the activation status of tumor‐infiltrating T cells, we queried the RNA sequencing data for the expression of a panel of effector and exhaustion markers (Wherry & Kurachi, 2015; Winkler & Bengsch, 2019) and observed prominent acquisition of an exhausted T‐cell phenotype in both CD4+ and CD8+ T cells in BrM (Fig 2H). This evidence concerns the gene CD4 and neoplasm.